Trajenta 5mg
Original price was: ₨ 7,000.₨ 6,500Current price is: ₨ 6,500.
Brand Name: Boehringer Ingelheim (co-marketed with Eli Lilly)
Chemical Name: Linagliptin
Dosage Strength: 5mg film-coated tablet
Rx/OTC: Prescription only (Rx)
Key Benefits of Trajenta 5mg
How It Works
- Linagliptin is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Blocks the enzyme that degrades GLP-1 and GIP incretin hormones.
- Increased active incretins enhance glucose-dependent insulin release from beta cells.
- Simultaneously reduces glucagon output from alpha cells, lowering fasting and postprandial glucose.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Recommended dose: 5mg once daily, with or without food.
- No dose adjustment needed for renal or hepatic impairment.
- When added to a sulfonylurea or insulin, consider lowering the companion drug to reduce hypoglycemia risk.
- Missed dose: take as soon as remembered; never double up.
Uses:
- Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- Can be used as monotherapy or in combination with other antidiabetic agents including metformin, sulfonylureas, or insulin.
- Not indicated for type 1 diabetes or diabetic ketoacidosis.
- Particularly suitable for patients with renal or hepatic impairment, as no dose adjustment is required.
Possible Side Effects:
- Common: nasopharyngitis, headache, elevated lipase levels.
- Serious: acute pancreatitis (including fatal cases), severe hypersensitivity (anaphylaxis, angioedema, exfoliative skin conditions), bullous pemphigoid.
- Joint pain and hypoglycemia when combined with sulfonylureas/insulin.
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Frequently Asked Questions
It is generally weight-neutral, unlike some other diabetes medications.
No. Linagliptin is primarily eliminated via the bile and gut, so kidney function does not affect dosing.
Yes. It is frequently prescribed alongside metformin when monotherapy is insufficient.
Severe abdominal pain (possible pancreatitis), blistering skin rash, or swelling of the face/tongue stop the drug and seek medical help.
Trajenta 5mg price in Pakistan at the medicine store is ₨ 6,500.
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