Seroquel 25mg
Original price was: ₨ 3,300.₨ 3,000Current price is: ₨ 3,000.
Brand Name: AstraZeneca
Chemical Name: Quetiapine fumarate
Dosage Strength: 25mg immediate-release tablet
Rx/OTC: Prescription only (Rx)
Seroquel 25mg is a prescription tablet from the atypical antipsychotic class, used to treat schizophrenia and bipolar I disorder (mania, depression, and maintenance). It works mainly by balancing dopamine and serotonin signals in the brain, which helps reduce psychotic symptoms and stabilise mood. Drowsiness is common in the first week, and it should never be stopped suddenly without a doctor’s guidance.
Key Benefits of Seroquel 2mg
How It Works
- Quetiapine is an atypical (second-generation) antipsychotic.
- Antagonises dopamine D2 and serotonin 5-HT2A receptors in the brain.
- Also blocks H1 (histamine), alpha-1 adrenergic, and 5-HT1A receptors, which contribute to its sedative and mood-stabilising effects.
- Restores neurotransmitter balance to reduce psychotic symptoms and stabilise mood.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Schizophrenia (adults): 25mg twice daily on Day 1, titrated to a target of 300–400mg/day in 2 divided doses.
- Bipolar mania: typically 100mg/day on Day 1, increased to 400mg/day by Day 4.
- Bipolar depression: 50mg at bedtime, titrated to 300mg at bedtime by Day 4.
- Take with or without food. Swallow whole; do not crush or chew.
Uses:
- Treatment of schizophrenia in adults and adolescents (13–17 years).
- Acute manic and depressive episodes in bipolar I disorder.
- Maintenance treatment of bipolar I disorder (as adjunct to lithium or divalproex).
- Adjunctive treatment of major depressive disorder (extended-release form).
Possible Side Effects:
- Common: somnolence, dizziness, dry mouth, constipation, weight gain, orthostatic hypotension.
- Serious: metabolic changes (hyperglycaemia, dyslipidaemia), neuroleptic malignant syndrome, tardive dyskinesia, QT prolongation.
- Boxed warnings: increased mortality in elderly patients with dementia-related psychosis; increased risk of suicidal thoughts in patients aged ≤24 years.
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Frequently Asked Questions
No. Alcohol increases sedation and impairs cognition; avoid it during treatment.
Yes, somnolence is common, especially during the first week and after dose increases.
No. Abrupt discontinuation can cause insomnia, nausea, and dizziness. Taper under medical supervision.
Yes, weight gain and metabolic changes can occur. Periodic monitoring of weight, lipids, and glucose is recommended.
Seroquel 25mg tablet price in Pakistan at Medicine Store is ₨ 3,000.
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