Januvia 100mg
₨ 5,800
Brand Name: Merck Sharp & Dohme (MSD)
Chemical Name: Sitagliptin (as sitagliptin phosphate)
Dosage Strength: 100mg film-coated tablet
Rx/OTC: Prescription only (Rx)
Januvia 100mg is a once-daily oral DPP-4 inhibitor that helps adults with type 2 diabetes control blood sugar alongside diet and exercise. It works by raising the body’s natural incretin hormones so insulin is released only when blood sugar is high. The dose must be reduced if you have moderate or severe kidney disease.
Key Benefits of Januvia 100mg
How It Works
- Sitagliptin is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Inhibits DPP-4, increasing active levels of incretin hormones (GLP-1 and GIP).
- This stimulates glucose-dependent insulin release and suppresses glucagon, lowering fasting and postprandial glucose with low risk of hypoglycaemia.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Standard dose: 100mg once daily, with or without food.
- Moderate renal impairment (eGFR 30 to <45): 50mg once daily.
- Severe renal impairment (eGFR <30) or end-stage kidney disease: 25mg once daily.
- Take at the same time each day.
Uses:
- Adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus.
- Used as monotherapy or in combination with metformin, sulfonylureas, thiazolidinediones, or insulin.
Possible Side Effects:
- Common: upper respiratory tract infection, headache, nasopharyngitis.
- Serious: acute pancreatitis, severe joint pain, hypersensitivity (anaphylaxis, angioedema, Stevens-Johnson syndrome), bullous pemphigoid, heart failure (in some studies with related agents).
Customer Reviews
They have already used our services
Frequently Asked Questions
Rarely on its own; risk increases when combined with sulfonylureas or insulin.
No. Sitagliptin is generally weight-neutral, unlike sulfonylureas or insulin.
Yes, but the dose must be reduced based on kidney function.
Stop the medication and seek medical care immediately, as this may indicate pancreatitis.
Januvia 100mg price in Pakistan at Medicine Store is ₨ 5,800.
Reviews
There are no reviews yet.