Xolair Injection 150mg
Original price was: ₨ 50,000.₨ 45,000Current price is: ₨ 45,000.
Brand Name: Novartis / Genentech (Roche)
Chemical Name: Omalizumab (Recombinant Humanised Anti-IgE Monoclonal Antibody)
Dosage Strength: 75mg/0.5mL and 150mg/1mL subcutaneous injection
Rx / OTC: Rx
A Xolair injection provides targeted biologic relief for patients suffering from moderate to severe persistent allergic asthma and chronic hives. Key omalizumab uses involve binding to IgE antibodies in the blood, stopping allergic reactions before they trigger severe asthma attacks. Because it is a specialized biologic, patients should consult their allergist about the Xolair injection price in Pakistan. Securing your monthly dose is easier when you verify the omalizumab price in Pakistan through medcinestore.pk, an authorized healthcare distributor.
Key Benefits of Xolair 150 Inj
How It Works
- Allergic reactions begin when immunoglobulin E (IgE) binds to mast cells and basophils, triggering the release of inflammatory chemicals that cause symptoms.
- Omalizumab binds directly to free IgE in the bloodstream, capturing it before it ever reaches those trigger cells.
- With IgE neutralised, the allergic cascade has no starting point.
- The immune system’s overreaction is stopped at its very first step, not after symptoms have already begun.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Administered by subcutaneous injection by a healthcare professional in a clinical setting.
- For allergic asthma: dose ranges from 75mg to 600mg every 2 to 4 weeks, calculated from your total serum IgE level and body weight using a specific dosing table.
- For chronic spontaneous urticaria: 300mg every 4 weeks regardless of IgE level.
- Patients must remain observed after each injection due to the risk of delayed anaphylaxis.
Uses:
- Treats moderate-to-severe persistent allergic asthma that does not respond adequately to inhaled corticosteroids.
- Approved for chronic spontaneous urticaria, persistent hives that antihistamines alone cannot control.
- Also indicated for chronic rhinosinusitis with nasal polyps.
- Co-developed by Novartis and Genentech; targets the root cause of allergic disease rather than just managing symptoms.
Possible Side Effects:
- Injection site reactions and mild headache are the most commonly reported side effects.
- Anaphylaxis is rare but possible and can occur up to 4 days after the injection.
- All patients must be prescribed and trained to use an adrenaline auto-injector for home emergency use.
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