Xarelto 10mg
₨ 4,250
Brand Name: Bayer (co-marketed with Janssen in some regions)
Chemical Name: Rivaroxaban
Dosage Strength: 10mg film-coated tablet
Rx/OTC: Prescription only (Rx)
Xarelto 10mg is a once-daily oral blood thinner that blocks factor Xa to help prevent dangerous clots. The 10mg dose is mainly used to prevent blood clots after hip or knee replacement surgery, and to prevent recurrence after a DVT or PE has already been treated. The 10mg tablet can be taken with or without food, and routine INR blood tests are not needed.
Key Benefits of Xarelto 10mg
How It Works
- Rivaroxaban is a direct, selective, oral inhibitor of factor Xa.
- Factor Xa converts prothrombin to thrombin in the coagulation cascade.
- By inhibiting Xa, rivaroxaban interrupts thrombin generation and clot formation, reducing the risk of arterial and venous thrombosis.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- VTE prophylaxis after hip replacement: 10mg once daily for 5 weeks, starting 6–10 hours postoperatively.
- VTE prophylaxis after knee replacement: 10mg once daily for 2 weeks.
- Extended VTE prevention: 10mg once daily after at least 6 months of treatment with a higher therapeutic dose.
- 10mg can be taken with or without food.
Uses:
- Prevention of venous thromboembolism (VTE) in adults after elective hip or knee replacement surgery.
- Extended treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) to prevent recurrence after at least 6 months of standard therapy.
- Reduction of cardiovascular risk in chronic coronary artery disease or peripheral artery disease, in combination with low-dose aspirin (2.5mg dose; 10mg not used here).
Possible Side Effects:
- Common: bleeding (nosebleed, gum bleeding, bruising, heavy menstruation), anaemia, nausea.
- Serious: major bleeding (gastrointestinal, intracranial), spinal/epidural haematoma with neuraxial procedures.
- Boxed warnings: premature discontinuation increases thrombotic risk; risk of spinal/epidural haematoma in patients undergoing neuraxial anaesthesia or spinal puncture.
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Frequently Asked Questions
The 10mg tablet can be taken with or without food. The 15mg and 20mg tablets must be taken with food for full absorption.
Take it as soon as you remember it on the same day, then continue normally. Do not double the dose.
Yes. Andexanet alfa is approved for reversing rivaroxaban-induced bleeding; prothrombin complex concentrates may also be used.
Combination significantly increases bleeding risk. Use only when specifically prescribed.
Xarelto 10mg price in Pakistan at Medicine Store is ₨ 4,250.

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