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Tegral 200mg
Original price was: ₨ 2,800.₨ 2,400Current price is: ₨ 2,400.
Brand Name: Novartis Pharma Pakistan Ltd.
Chemical Name: Carbamazepine
Dosage Strength: 200mg film-coated tablets
Rx / OTC: Rx
Description
Tegral 200mg Tablets
Tegral 200mg is a Novartis-manufactured anticonvulsant. This is prescribed for generalised tonic-clonic and partial seizures, trigeminal neuralgia, and bipolar disorder unresponsive to lithium. It works by stabilising overactive nerve cells through sodium channel blockade, calming abnormal electrical signals in the brain. Available as 200mg film-coated tablets, it requires gradual dose titration and regular blood monitoring during treatment. Backed by decades of clinical use, Tegral remains a trusted first-line therapy for epilepsy and neuropathic pain worldwide.
Key Benefits of Tegral 200mg
Trusted Novartis formulation with decades of clinical evidence across multiple neurological conditions
Effective in controlling several seizure types and neuropathic pain with a single medicine.
Flexible oral dosing allows individual titration for best symptom control.
How It Works
- Seizures and nerve pain episodes are driven by abnormal, repetitive electrical firing across neurons.
- Carbamazepine stabilises neuronal membranes by blocking voltage-gated sodium channels, reducing high-frequency repetitive firing.
- This limits the spread of seizure activity from the focus and dampens abnormal nerve signalling in trigeminal neuralgia.
- The result is steady neurological control without fully sedating the central nervous system.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Adults typically start at 100–200mg once or twice daily, gradually increased to 800–1200mg daily in divided doses.
- For trigeminal neuralgia, dosing usually reaches 200mg three to four times daily before tapering to the lowest effective maintenance dose.
- Take with food to reduce stomach upset and maintain consistent absorption.
- Patients of Han Chinese and Thai origin should be screened for HLA-B*1502 before starting due to the increased risk of severe skin reactions.
Uses:
- Prescribed for generalised tonic-clonic and partial seizures in adults and children with epilepsy.
- Relieves the sharp, episodic nerve pain of trigeminal neuralgia and glossopharyngeal neuralgia.
- Used as prophylaxis in manic-depressive psychosis in patients unresponsive to lithium therapy.
- Manufactured by Novartis Pharma Pakistan Ltd., one of the most established anticonvulsants in clinical use worldwide.
Possible Side Effects:
- Common: dizziness, drowsiness, nausea, unsteady gait, dry mouth, and blurred vision often settle with continued use.
- Serious but less common: severe skin reactions (Stevens-Johnson syndrome), low sodium levels, blood count changes, and liver enzyme elevation.
- Regular blood tests are recommended to monitor liver function and blood counts throughout treatment.
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Frequently Asked Questions
How long does Tegral 200mg take to control seizures?
Symptoms often improve within 1–2 weeks or once stable therapeutic blood levels are reached.
Can I stop Tegral suddenly?
No. Abrupt withdrawal can trigger seizures. Any dose change must be done gradually under medical supervision.
Does Tegral interact with other medicines?
Yes, carbamazepine induces liver enzymes and can reduce the effectiveness of hormonal contraceptives, warfarin, and many other drugs.
Can Tegral be used during pregnancy?
Carbamazepine has been linked to congenital malformations, including spina bifida. Use only if the benefit clearly outweighs the risk, under specialist supervision.
How should I store Tegral tablets?
Store below 30°C in a dry place, protected from moisture and light.
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