Buy Aromasin 25mg Tablets in Pakistan
Original price was: ₨ 10,250.₨ 9,800Current price is: ₨ 9,800.
Medicine Name: Aromasin 25mg Tablets
Brand Name: Pfizer Inc.
Chemical Name: Exemestane (Steroidal Aromatase Inactivator)
Dosage Strength: 25mg sugar-coated tablets
Rx / OTC: Rx
Aromasin
Aromasin 25mg is a crucial part of post-surgery therapy for postmenopausal women battling hormone-dependent breast cancer. The primary exemestane uses involve permanently disabling the aromatase enzyme to cut off the estrogen supply that fuels tumor growth. Taking one Aromasin tablet daily significantly lowers the chances of the breast cancer returning in the years following treatment. Patients should consult their oncologist and check the current Aromasin tablet price in Pakistan to secure their long-term supply.
Key Benefits
Irreversible aromatase inactivation provides deep, sustained oestrogen suppression.
Sequential strategy after tamoxifen significantly reduces breast cancer recurrence risk.
25 years of global clinical data supporting Pfizer's established oncology formulation.
How It Works
- After menopause, oestrogen is no longer produced by the ovaries; instead, it is manufactured through peripheral aromatisation of adrenal androgens.
- Exemestane binds irreversibly to the aromatase enzyme and permanently destroys its activity this is known as “suicide inhibition.”
- Unlike reversible inhibitors, this permanent inactivation means oestrogen cannot be resynthesised until the body produces entirely new aromatase enzyme.
- The result is deeper, more sustained oestrogen suppression compared to reversible aromatase inhibitors.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Take one 25mg tablet once daily after a meal. Food increases exemestane bioavailability by approximately 40% compared to fasting.
- Taking it consistently after eating is important for maintaining consistent drug levels throughout treatment.
- Swallow the tablet whole.
- Your oncologist determines the duration of treatment in the adjuvant setting typically continuing until the 5-year hormonal treatment course is complete.
Uses:
- Prescribed for postmenopausal women with hormone receptor-positive breast cancer.
- Used as adjuvant treatment after 2 to 3 years of tamoxifen therapy to complete a total 5-year hormonal treatment course.
- Also prescribed for advanced breast cancer that has progressed on prior anti-oestrogen treatment.
- Manufactured by Pfizer, exemestane permanently inactivates the aromatase enzyme that produces oestrogen, cutting off the hormonal fuel that drives hormone-sensitive breast cancer growth.
Possible Side Effects
- Hot flushes, joint pain, fatigue, and night sweats are the most common side effects, all of which reflect the reduced oestrogen environment.
- Bone mineral density loss is an important long-term concern. Baseline DEXA scanning, annual monitoring, and daily calcium and vitamin D supplementation are standard practices throughout treatment.
- Arthralgia (joint pain) can be treatment-limiting for some patients. Discuss this with your oncologist if it is affecting daily life.
If you experience sudden vision/hearing loss or an erection lasting longer than 4 hours, seek urgent medical help.
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