Zoladex Injection
Original price was: ₨ 16,500.₨ 14,900Current price is: ₨ 14,900.
Brand Name: AstraZeneca (imported from Turkey)
Chemical Name: Goserelin Acetate
Dosage Strength: 3.6mg subcutaneous implant in a pre-filled syringe
Rx / OTC: Rx
Zoladex 3.6mg by AstraZeneca is a monthly subcutaneous implant containing goserelin acetate, an LHRH agonist used in advanced prostate cancer, breast cancer in pre-menopausal women, endometriosis, and endometrial thinning. It works by suppressing pituitary hormones, lowering testosterone in men and oestradiol in women to slow hormone-sensitive tumour growth. Administered every 28 days into the abdominal wall by a healthcare professional, the biodegradable implant fully dissolves between doses. Backed by decades of clinical evidence in oncology and gynaecology.
Key Benefits Of Zoladex Inj
How It Works
- Zoladex is a synthetic LHRH (GnRH) agonist that, on continuous use, suppresses the pituitary release of LH and FSH.
- This suppression dramatically reduces testosterone production in men and oestradiol production in women.
- Hormone-sensitive prostate and breast cancer cells depend on these sex hormones for growth removing the hormonal fuel slows tumour progression.
- In endometriosis, low oestrogen causes the endometriotic lesions to regress over the treatment period.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- One 3.6mg implant is injected subcutaneously into the anterior abdominal wall every 28 days.
- Administered by a healthcare professional, never self-injected.
- No dose adjustment is needed for renal or hepatic impairment, or in the elderly.
- Treatment for endometriosis and endometrial thinning should not exceed 6 months.
Uses:
- Advanced prostate cancer palliative treatment, in combination with flutamide, for locally confined prostate carcinoma.
- Advanced breast cancer in pre- and perimenopausal women, and in combination with hormonal therapy for early breast cancer.
- Endometriosis pain relief and reduction of endometriotic lesions during therapy.
- Endometrial thinning before endometrial ablation for dysfunctional uterine bleeding.
Possible Side Effects:
- Initial “tumour flare” in cancer patients during the first weeks is due to a transient testosterone or oestrogen rise.
- Common: hot flushes, sweating, reduced libido, injection-site reactions, and mood changes.
- Long-term use reduces bone mineral density monitoring and supportive therapy may be recommended.
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Frequently Asked Questions
Once every 28 days. Consistent dosing intervals are essential to maintain hormone suppression.
Store below 25°C in the original packaging, protected from light.
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