PROLIA (Denosumab) Injection 60mg
Original price was: ₨ 38,000.₨ 37,500Current price is: ₨ 37,500.
Medicine Name: Prolia 60mg Injection
Brand Name: Amgen Inc.
Chemical Name: Denosumab (Fully Human Anti-RANK Ligand Monoclonal Antibody)
Dosage Strength: 60mg/1mL prefilled syringe for subcutaneous injection
Rx / OTC: Rx
PROLIA Injection
Prolia is a revolutionary biannual treatment designed to significantly increase bone mass in postmenopausal women with high osteoporosis risk. Given as a quick denosumab injection just twice a year, it works by blocking the specific cells that break down your bone tissue. A single dose of Prolia 60 mg provides six months of continuous protection against debilitating bone fractures. Patients looking to invest in their bone health can ask their rheumatologist about the Prolia injection price in Pakistan.
Key Benefits Of Cialis 5mg Tablets
Just two injections per year for continuous, sustained fracture protection.
Proven to reduce hip, vertebral, and non-vertebral fracture risk in major clinical trials.
Targets RANK Ligand, the master regulator of bone loss, with precision monoclonal antibody technology.
How It Works
- In osteoporosis, bone is constantly broken down by osteoclasts and rebuilt by osteoblasts. In osteoporosis, destruction outpaces rebuilding.
- RANK Ligand is the signal molecule that activates osteoclasts and drives accelerated bone destruction.
- Denosumab binds directly to RANK Ligand and blocks it completely, reducing osteoclast activity and slowing bone resorption.
- With osteoclast activity suppressed, bone mineral density recovers and strengthens progressively over time.
Dosage, Uses & Possible Side Effects
Dosage & Administration:
- Given as a single 60mg subcutaneous injection once every 6 months, into the abdomen, upper thigh, or upper arm by a healthcare professional.
- Daily calcium and vitamin D supplementation is mandatory throughout treatment to prevent dangerous hypocalcaemia.
- Never stop Prolia without a physician-supervised transition plan; abrupt discontinuation causes a rapid rebound in bone resorption.
- Stopping without transitioning to another bone-protective therapy carries a significant risk of multiple vertebral fractures.
Uses:
- Prescribed for postmenopausal women and men with osteoporosis at high fracture risk.
- Used for patients losing bone density due to hormone deprivation therapy in prostate or breast cancer treatment.
- Reduces vertebral, hip, and non-vertebral fracture risk with just two injections per year.
- Manufactured by Amgen Inc., a precision biologic targeting the core mechanism of bone loss.
Possible Side Effects:
- Back pain, musculoskeletal pain, and mild hypocalcaemia are the most commonly reported side effects.
- Hypocalcaemia must be corrected before starting Prolia. Low calcium is a direct contraindication to treatment.
- Rare but serious long-term risks include osteonecrosis of the jaw and atypical femoral fractures.
If you experience sudden vision/hearing loss or an erection lasting longer than 4 hours, seek urgent medical help.
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