Prograf 1mg (Tacrolimus) Price in Pakistan
Original price was: ₨ 10,250.₨ 9,850Current price is: ₨ 9,850.
Medicine Name: Prograf 1mg Capsules
Brand Name: Astellas Pharma
Chemical Name: Tacrolimus (FK506)
Dosage Strength: 0.5mg, 1mg, and 5mg hard capsules
Rx / OTC: Rx
Prograf
Prograf 1mg is a life-saving immunosuppressive medication essential for patients who have recently undergone liver, kidney, or heart transplants. By utilizing the active ingredient tacrolimus, it precisely suppresses the immune system to prevent the body from rejecting the new organ. Each prescribed tacrolimus tablet must be taken exactly on schedule to maintain safe and consistent levels in the bloodstream. Transplant recipients can coordinate with specialized pharmacies to verify the Prograf 1mg price in Pakistan for long-term care.
Key Benefits Of Cialis 5mg Tablets
Gold-standard calcineurin inhibitor in global transplant medicine for over 25 years.
Targeted T-cell suppression with precise therapeutic drug level monitoring.
Available in multiple strengths for accurate, individualised transplant dosing.
How It Works
- Tacrolimus binds to the intracellular protein FKBP-12 inside T-lymphocytes.
- The resulting complex blocks calcineurin, a critical signalling enzyme that would otherwise trigger T-cells to produce interleukin-2 and mount a full immune attack on the transplanted organ.
- By interrupting this single step in the rejection pathway, Prograf stops rejection without shutting the entire immune system down.
- Regular blood level monitoring ensures the drug stays within the narrow range that is both effective and safe.
Dosage , Uses & Possible Side Effects
Dosage & Administration:
- Take Prograf exactly 12 hours apart, twice daily, at the same times every day without exception.
- Take it consistently, either always with food or always without food, alternating between the two alters absorption and destabilises blood levels.
- Avoid grapefruit and grapefruit juice completely throughout therapy, as they block the enzyme that metabolises tacrolimus and can cause dangerous blood level spikes.
- Swallow capsules whole, do not open, crush, or chew them.
Uses:
- Prescribed following kidney, liver, and heart transplantation to prevent the immune system from rejecting the transplanted organ.
- Also used to treat acute rejection episodes that have not responded to other immunosuppressive treatments.
- One of the most widely used and clinically important immunosuppressants in modern transplant medicine.
- Manufactured by Astellas Pharma, with over 25 years of transplant use globally.
Possible Side Effects:
- Kidney function changes, elevated blood pressure, and blood sugar disturbances are the most clinically significant, all are dose-related and closely monitored.
- Tremor, headache, and increased susceptibility to infection are also commonly reported.
- Never adjust your dose without direct instruction from your transplant team.
If you experience sudden vision/hearing loss or an erection lasting longer than 4 hours, seek urgent medical help.
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